The Dose

FDA removes menopause therapy black box warnings
FAQs: Menopause hormone therapy
Non-hormonal therapies for vasomotor symptoms of menopause (VMS): boon or bust?
New products on the market: Pylera, Anzupgo
Rapid fire updates: Vortioxetine (Trintillex) is now generic, ODB coverage for Inclisiran (Leqvio), biologic drug approval for COPD (dupilumab), finerenone new indication for heart failure
Practice tool spotlight: CKD Pathway
Hospital discharge case: Cocktails to avoid ordering

BEDMED: Does time of day matter for antihypertensives?
RSV program now includes adults 75+
All bark and no bite: evidence for inhalers in acute cough
Practice tool spotlight: Menopausal hormone therapy equivalency table
ODB coverage update: Slynd (drosperinone) is covered
Rapid fire updates: Diabetes Canada updated CKD guideline, 2025 Obesity Canada guidelines
CEP detailing updates: New topic – menopause
Cover your bases: quadruple regimens for H. pylori eradication

What weight loss medications are available in Canada and what do they cost?
How do I switch between injectable weight loss medications?
What is the cheapest injectable weight loss medication? Any cost savings or coverage?

Zepbound (tirzepatide) – new option for weight loss
Dexcom G7 and FreeStyle Libre 3 Plus
Continuous glucose monitors (CGMs): What you need to know
Practice tool spotlight: Calcium Calculator
Rapid fire updates: Saxenda discontinuation, Hypertension Canada 2025 guidelines, Rupall generic
CEP academic detailing – New topic: ADHD in adults
New products on the market: Bijuva, Pyridium, Accrufer
Treating lice in primary care

Cardiovascular outcomes of lipoprotein a [Lp(a)] and apoprotein B [ApoB]
NACI updates HPV vaccination schedules
Metformin can be continued in stage 3 and 4 CKD
Practice tool spotlight: LiverTox
Rapid fire updates: Mounjaro pens, GLP-1 RA and risk of self-harm, Provera and Depo-Provera risk of meningioma
CEP academic detailing updates – New topic: ADHD in adults
New products on the market: Ixchiq, Veozah, Winlevi
Case: Optimizing meds post NSTEMI
Lp(a) and ApoB: what are they and when to order?

The Dose Fall 2024 table of contents:

Pneumococcal vaccine coverage updates
ODB transitions to biosimilars of Prolia and Xgeva
RSV season is here!
Practice tool spotlight: Essential Medicines Program
New products on the market: Jubbonti, Evenity, Insujet
Rapid fire updates: Diabetes Canada guideline update, 2024 BPSD guidelines, DOACs now covered by ODB
CEP academic detailing updates – New topic: Weight management
Are all DOACs created equal?
Pneumococcal vaccines FAQs
RSV vaccines FAQs

Finding the silver lining in drug shortages
LifeLabs updates eGFR calculation
Surgery? Pregnancy? What to do about GLP-1 agonists
Practice tool spotlight: Bugs and Drugs 2.0
New drugs that have caught our attention: Quviviq, Ryaltris, Awiqli
Rapid fire updates: Paxlovid evidence and coverage, Wegovy available, CANMAT 2023 depression guideline update, Depo Provera lots and expiries
Something’s fishy: sustainability of omega-3 supplements
CEP academic detailing updates
New nicotine replacement you may not have heard about
Beyond cigarettes: talking about vaping cessation

Two guideline updates you should know about
- PEER (Patients Experience Evidence Research) Simplified Lipid Guideline
- Canadian Osteoporosis Guideline
Climate conscious inhaler prescribing: How do I initiate a “greener” practice in my own patients who have never been prescribed an inhaler before?
Caring for trans patients in primary care part 3: masculinizing hormone therapy
Practice tip: reconciling minor ailments prescribing in the EMR
Appendices:
- PEER 2-page graphical summary
- Osteoporosis algorithms
- Ozempic LU criteria message

The Dose Fall 2023: table of contents:

An introduction to providing inclusive primary care to trans patients
Finerenone (Kerendia) for secondary cardiorenal risk reduction in type 2 diabetes
Academic detailing update: Anxiety and depression
Answers to common questions about treatments for allergic rhinitis
Pharmacy practice update: administration of substances by inhalation and injection
Rethinking menopausal hormone therapy

Saving the world, one canister at a time: climate conscious inhaler prescribing
To treat or not to treat? Risk and benefits of treatments for acute cough
Should you try out the new tri-ple therapy inhaler, Breztri?
Community pharmacist update: Minor Ailments Prescribing – happening now!
Odds and Ends: new generics, ODB formulary updates
A 5-point Refresher on Biosimilars
A comparison of trials using SGLT2 inhibitors for chronic kidney disease
Drug Information Tool Spotlight: Support probiotic recommendations with evidence using probioticchart.ca
Ubrelvy® (ubrogepant) Drug Summary

See below for previous editions of The Dose!

Contact Information